Search on: VACCINES, CONJUGATE 
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Descriptor English:   Vaccines, Conjugate 
Descriptor Spanish:   vacunas conjugadas 
Descriptor Portuguese:   Vacinas Conjugadas 
Synonyms English:   Conjugate Vaccines  
Tree Number:   D20.215.894.865.900
D23.050.865.900
Definition English:   Semisynthetic vaccines consisting of polysaccharide antigens from microorganisms attached to protein carrier molecules. The carrier protein is recognized by macrophages and T-cells thus enhancing immunity. Conjugate vaccines induce antibody formation in people not responsive to polysaccharide alone, induce higher levels of antibody, and show a booster response on repeated injection. 
Indexing Annotation English:   "induce antibody formation in people not responsive to polysaccharide alone"; semisynthetic vaccines; coord NIM with specific vaccine (IM)
History Note English:   94 
Allowable Qualifiers English:  
AD administration & dosage AE adverse effects
AN analysis BI biosynthesis
BL blood CF cerebrospinal fluid
CH chemistry CL classification
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism MI microbiology
PD pharmacology PO poisoning
RE radiation effects ST standards
TU therapeutic use TO toxicity
UL ultrastructure UR urine
VI virology  
Record Number:   30984 
Unique Identifier:   D018074 

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